黑色素瘤(melanoma)

黑色素瘤屬於皮膚癌中最嚴重的一種惡性腫瘤,一般來說其呈現的形式有三種,包括平面、鼓起(形成結節)、傷口(潰瘍)等,黑色素瘤的發生率和發生的形式與人種有關,一般來說,白種人的發生率遠高於黃種人和黑人,而黃種人好發的肢端型黑色素瘤在白種人中卻是發生率做低的
一、分類
A. 表淺擴散型(superficial spreading melanoma):
a. 大約占70%
b. 常見於外國人,特別容易出現在曬太陽的部位
c. 應盡早切除
B. 結節型(Nodular melanoma):
a. 大約占15%
b. 大多垂直生長
c. 容易被誤認為腫瘤,切掉後才發現是黑色素瘤
C. 肢端痣樣型(Acral lentiginous melanoma):
a. 大約占8%
b. 皮膚黑一點的比較常見,是台灣人最常見的一種
c. 出現在沒有曬太陽的部位,例如:腳趾縫、腳底、背部等等。
d. 通常不痛不癢易被忽略
D. 惡性痣型(Lentigo maligna melanoma):
a. 常發生在老年人
b. 大型表淺擴散的黑色素瘤(放射狀生長)
資料來源:高雄榮民總醫院
二、檢驗
 s100:非專一性(non-specific),用來篩檢黑色素瘤,也可染神經物質的腫瘤
 HMB45:專一性(specific),也可染淋巴腺轉移
 melan A:專一性(specific)
▼表皮(epidermis) 顯示/隱藏(show/hide)

1 意見:

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