人類白細胞抗原疾病(human leukocyte antigen, HLA related disease)

HLA Class II Effects		AUTOIMMUNE DISEASE	HLA Class I Effects
Predisposing	Protective		Predisposing	Protective
◊	◊	Ankylosing spondylitis	B*2701 B*2704 B*2705	B*2706 B*2709
DR3 DRB1*08	DR7	Graves’ disease	C*07 B*08	C*16 C*03 B*44
DR4 DR3	DR7	Hashimoto’s thyroiditis	◊	◊
DR3	◊	Myasthenia Gravis	◊	◊
DR3	◊	Addison’s disease	◊	◊
Shared epitope = DRB1*0101 DRB1*0102 DRB1*0401 DRB1*0404 DRB1*0405 DRB1*0408 DRB1*1001 DRB1*1402	DRB1*0103 DRB1*07 DRB1*1201 DRB1*1301 DRB1*1501	Rheumatoid arthritis	◊	◊
DQ2 DQ8	◊	Celiac disease	◊	◊
DR15	DR14	Multiple sclerosis	C*05 C*15	C*01
DR3 DR4 DQB1 position β57	DR15 DR14	Type 1 diabetes	B*39 B*18 A*24	A*01 A*11 A*31
DR3 DR8 DR15	◊	Systemic lupus erythematosus	◊	◊

資料來源：NCBI

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